Hydroxyprogesterone
(17-alpha Hydroxyprogesterone Caproate)

Hydroxyprogesterone.com

NEJM Abstract

17-p Progesterone declared SAFE Article

NEJM Full-Text Article

NEJM Editorial

AJOG-Study

Hydroxyprogesterone Safety

Hydroxyprogesterone Links

Where can I find
17-Alpha Hydroxyprogesterone?

This site shares information from a variety of sources about the prescription medication 17-alpha hydroxyprogesterone caproate. This medication, also known as 17P (Hydroxyprogesterone), received much recent attention as researchers indicate it may show promise in reducing the incidence of preterm birth in high risk pregnancies.

Once commercially available in the United States from major manufacturers, 17P (Hydroxyprogesterone) is currently available only by prescription from specialty pharmacies that compound sterile products.

The information on this web site is not intended as medical advice.
If you are at risk for preterm birth and would like more information, please see your doctor.

What is 17alpha Hydroxyprogesterone Caproate?

(also 17-AHPC, 17P)

C27 H40 O4 = 428.6

Pharmacopoeial Description:
USP 25: A white or creamy-white, crystalline powder. Odourless or having a slight odour. Insoluble in water; soluble in ether; slightly soluble in benzene. Protect from light.

Uses and Administration:
Hydroxyprogesterone caproate is a progestogen structurally related to progesterone that has been used for recurrent miscarriage and various menstrual disorders. In recurrent miscarriage associated with proven progesterone deficiency, suggested doses have been 250 to 500 mg weekly by intramuscular injection during the first half of pregnancy.

(The Complete Drug Reference. Martindale, Pharmaceutical Press. Thirty-third edition. 2002 p. 1479)